1,8Cineole1,8 Cineole Molecule

Welcome to this week’s episode of the Aromatic Wisdom Podcast!
This week, I continue with our September theme of Allergies and Respiratory Health and talk about how knowing a little essential oil chemistry can empower you to choose essential oils that support your respiratory system. We take a close look at the therapeutic properties of the molecule, 1,8 cineole, the essential oils that have a high content of it, and how you can use those oils to support all sorts of respiratory discomforts.  It’s a great episode.

Enjoy the podcast!  It is my sincere hope that you will feel inspired to explore essential oils deeper after listening and learn what is possible when for your health and well-being when you include aromatherapy into your life.

Links and Resources Mentioned in Episode 14

Essential Oils High in 1,8 Cineole 

  • Cardamom – Ellettaria cardamomum
  • Eucalyptus – both Eucalyptus globulus and Eucalyptus radiata
  • Helichrysum gymnocephalum (This oil is usually just referred to by its full Latin name)
  • Myrtle – Myrtus communis
  • Niaouli ct. 1,8 cineole – Melaleuca quinquenervia ct 1,8 cineole
  • Rosalina – Melaleuca ericifolia
  • Saro  – Cinnamosma fragrans
  • Spike Lavender – Lavendula latifolia
  • Laurel Leaf – Laurus nobilis
  • Ravintsara – Cinnamomum camphor ct 1,8 cineole
  • Rosemary ct 1,8 cineole – Rosmarinus officinalis ct 1,8 cineole

1,8 Cineole References 

  • Sato K, Krist S, Buchbauer G (2007) Antimicrobial effect of vapors of geraniol, (R)-(-)-linalool, terpineol, gamma-terpinene and 1,8-cineole on airborne microbes using an air washer. Flavour & Fragrance Journal 22:435-43
  • Santos FA, Rao VS (2000) Anti-inflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils. Phytotherapy Research 14:240-244
  • Liapi C, Anifandis G, Chinou I et al (2007) Antinociceptive properties of 1,8-cineole and beta-pinene, from the essential oil of Eucalyptus camaldulensis leaves, in rodents. Planta Medica 73:1247-1254
  • Pattnaik S, Subramanyam VR, Bapaji M et al (1997) Antibacterial and antifungal activity of aromatic constituents of essential oils. Microbios 89:39-46
  • Carson CF, Mee BJ, Riley TV (2002) Mechanism of action of Melaleuca alternifolia (tea tree) oil on Staphylococcus aureus determined by time-kill, lysis, leakage, and salt tolerance assays and electron microscopy. Antimicrobial Agents and Chemotherapy 46:1914-1920
  • Juergens UR, Dethlefsen U, Steinkamp G et al (2003) Anti-inflammatory activity of 1,8 cineole (eucalyptol) in bronchial asthma: a double-blind, placebo-controlled trial. Respiratory Medicine 97:250-256
  • Juergens UR, Engelen T, Racke K (2004) Inhibitory activity of 1,8-cineol (eucalyptol) on cytokine production in cultured human lymphocytes and monocytes. Pulmonary Pharmacology & Therapeutics 17:281-287
  • Santos FA, Silva RM, Campos AR et al (2004) 1,8-Cineole (eucalyptol), a monoterpene oxide attenuates the colonic damage in rats on acute TNBS-colitis. Food & Chemical Toxicology 42:579-584
  • Nascimento NR, Refosco RM, Vasconcelos EC (2009) 1,8-Cineole induces relaxation in rat and guinea-pig airway smooth muscle. Journal of Pharmacy & Pharmacology 61:361-366
  • Coelho-de-Souza LN, Leal-Cardoso JH, De Abreu Matos FJ et al (2005) Relaxant effects of the essential oil of Eucalyptus tereticornis and its main constituent 1,8-cineole on guinea-pig tracheal smooth muscle. Planta Medica 71:1173-1175
  • Bastos VP, Brito TS, Lima FJ et al (2009) Inhibitory effect of 1,8-cineole on guinea-pig airway challenged with ovalbumin involves a preferential action on electromechanical coupling. Clinical & Experimental Pharmacology & Physiology 36:1120-1126
  • Kako H, Fukumoto S, Kobayashi Y et al (2008) Effects of direct exposure of green odor components on dopamine release from rat brain striatal slices and PC12 cells. Brain Research Bulletin 75:706-712
  • Lahlou S, Figueiredo AF, Magalhaes PJ et al (2002) Cardiovascular effects of 1,8 cineole, a terpenoid oxide present in many plant essential oils, in normotensive rats. Canadian Journal of Physiology & Pharmacology 80:1125-1131
  • Pinto NV, Assreuy AM, Coelho-de-Souza AN et al (2009) Endothelium-dependent vasorelaxant effects of the essential oil from aerial parts of Alpinia zerumbet and its main constituent 1,8-cineole in rats. Phytomedicine 16:1151-1155
  • Kehrl W, Sonnemann U, Dethlefsen U (2004) Therapy for acute nonpurulent rhinosinusitis with cineole: results of a double-blind, randomized, placebo-controlled trial. 114:738-742
  • Tesche S, Metternich F, Sonnemann U et al (2008) The value of herbal medicines in the treatment of acute non-purulent rhinosinusitis. Results of a double-blind, randomized, controlled trial. European Archives of Oto-Rhino-Laryngology 265:1355-1359
  • Worth H, Schacher C, Dethlefsen U (2009) Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled double-blind trial. Respiratory Research 10:6
  • Astani A, Reichling J, Schnitzler P. (2010) Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research 24(5):673-679
  • Matthys H, de Mey C, Carls C et al  (2000) Efficacy and tolerability of myrtol standardized in acute bronchitis. A multi-center, randomized, double-blind, placebo-controlled parallel-group clinical trial vs. cefuroxime and ambroxol. Arzneimittelforschung 50:700-711
  • Meister R, Wittig T, Beuscher N, et al (1999) Efficacy and tolerability of myrtol standardized in long-term treatment of chronic bronchitis. A double-blind, placebo-controlled study. Study Group Investigators. Arzneimittelforschung 49:351-358
  • Saito Y, Shiga A, Yoshida Y et al (2004) Effects of a novel gaseous antioxidative system containing a rosemary extract on the oxidation induced by nitrogen dioxide and ultraviolet radiation. Bioscience Biotechnology & Biochemistry 68:781-786
  • Nasel C, Nasel B, Samec P, Schindler E et al (1994) Functional imaging of effects of fragrances on the human brain after prolonged inhalation. Chemcial Senses 19(4):359-364
  • https://roberttisserand.com/2012/03/rosemary-boosts-brain-power/

In this week’s Smell My Life segment, I share how I used a nasal inhaler to protect my immunity and my health on the airplane while traveling to the Alliance of International Aromatherapists conference in Denver, Colorado.

Check out my blog post How to Make a Nasal Inhaler to learn the recipe I made for my inhaler.

Q: Alexandra Nicklas wrote, “Hi! Loving your podcast!! Thanks so much! One question I have is in regards to your 2nd podcast which stated that essential oils and water should not be used as a body spray. I find that people often do this though. It is just water with essential oil, right? How do you make a simple body spray?”

A: Liz answered, “Two things to keep in mind are:
1) we don’t like to use essential oils directly on the skin too often for fear of developing sensitization and
2) water and oils don’t mix.
That means that when you spray a mixture of water and essential oils on the skin, you’re getting blobs of essential oil directly on the skin and you could experience irritation or, if you do it enough, eventual sensitization also know as contact dermatitis.  If you want to make a body spray with essential oils and water, be sure to add a blob of aloe vera gel in the bottle to help disperse the essential oils so the product becomes a uniform solution.”

I may just read yours on the air!




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